Disruption of white matter integrity and its relationship with cognitive function in non-severe traumatic brain injury
Date
10/11/2022
Authors
Aimi Nadhiah Abdullah, Asma Hayati Ahmad,
Rahimah Zakaria, Sofina Tamam,
Aini Ismafairus Abd Hamid, Wen Jia Chai, Hazim Omar2,
Muhammad Riddha Abdul Rahman, Diana Noma Fitzrol,
Zamzuri Idris, Abdul Rahman Izaini Ghani,
Wan Nor Azlen Wan Mohamad, Faiz Mustafar,
Muhammad Hafiz Hanafi, Mohamed Faruque Reza,
Hafidah Umar, Mohd Faizal Mohd Zulkifly,
Song Yee Ang, Zaitun Zakaria, Kamarul Imran Musa,
Azizah Othman, Zunaina Embong, Nur Asma Sapiai,
Regunath Kandasamy, Haidi Ibrahim,
Mohd Zaid Abdullah, Kannapha Amaruchkul,
Pedro Antonio Valdes-Sosa, Maria Luisa Bringas Vega,
Bharat Biswal, Jitkomut Songsiri, Hamwira Sakti Yaacob,
Putra Sumari, Nor Azila Noh, Azlinda Azman,
Paramjit Singh Jamir Singh and Jafri Malin Abdullah
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Abstract
Impairment in cognitive function is a recognized outcome of traumatic brain injury (TBI). However, the degree of impairment has variable relationship with TBI severity and time post injury. The underlying pathology is often due to diffuse axonal injury that has been found even in mild TBI. In this study, we examine the state of white matter putative connectivity in patients with non-severe TBI in the subacute phase, i.e., within 10 weeks of injury and determine its relationship with neuropsychological scores.
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Medicine, Health and Life Sciences